Molecular by PCR Testing

Stone Clinical Laboratories offers an advanced molecular testing solution for common infections using PCR technology. This advanced technology accurately and definitively identifies the exact causative pathogen by its DNA/RNA. By identifying the pathogen(s), clinicians can treat patients quicker with the appropriate diagnosis.

The Stone Way

Molecular Testing by PCR – the better solution

  • Identifies causative organism/bacteria/pathogen by its DNA/RNA – which makes it possible to personalize diagnosis and treatment
  • 48 TAT, allowing for quicker treatment
  • Identifies poly-microbial infections
  • Traditional resistance gene mutations accompany UTI and wound patient results
  • Reduced risk of specimen contamination
  • >95% sensitivity and >95% specificity
  • Easy-to-interpret test results

Urinary Tract Infection Testing by PCR (UTI )

UTIs are among the most prevalent community acquired and hospital acquired infections, affecting almost 50% of the population at least once in their lifetime, and account for considerable amounts of morbidity and healthcare expenditure in the US, with an estimated annual cost of $3.5 billion.(1)

Traditional urine cultures missed 67% of uropathogens overall and 50% in the group with severe symptoms according to research published in the Journal of Clinical Microbiology; May 2016 T. Price et al.

Stone Clinical Laboratories UTI by PCR Testing

UTIs are among the most prevalent community acquired and hospital acquired infections, affecting almost 50% of the population at least once in their lifetime, and account for considerable amounts of morbidity and healthcare expenditure in the US, with an estimated annual cost of $3.5 billion.(1)

Traditional urine cultures missed 67% of uropathogens overall and 50% in the group with severe symptoms according to research published in the Journal of Clinical Microbiology; May 2016 T. Price et al.

UTI by PCR

  • UTI by PCR testing covers > 90% of the most common causative bacteria found in uncomplicated UTIs
  • >95% sensitivity and >95% specificity
  • Includes Resistance Gene Analysis to assist with therapeutic selection
  • Testing for broad range of organisms helps identify potential poly-infections due to multiple organism detection
  • 24 – 48 hour turn around time (TAT), allowing for quicker treatment

UTI requisition

UTI sample report

STD/STI Testing

Sexually transmitted diseases (STDs) are major causes of acute illness and infertility worldwide. The World Health Organization (WHO) estimates 499 million new cases of STDs occur annually worldwide in adults aged 15-49 years. The performance of nucleic acid amplification tests (PCR) with respect to overall sensitivity, specificity, and ease of specimen transport is better than that of any of the other tests available for the diagnosis of chlamydia and gonorrhea infections (1)

  • Stone Swab and Bacterial Vaginitis Panels by PCR offer extensive infection selection with high performance characteristics and an average of 24-48 hr. turn around time.
  • Stone Swab Comprehensive Panel includes testing of the following microorganisms:
    • Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes Simplex Virus 1, Herpes Simplex Virus 2, Human Papilloma Virus, Trichomonas vaginalis and Candida species
  • Bacterial Vaginitis Panel includes testing of the following microorganisms:
    • Bacterial vaginosis, trichomonas vaginalis, Candida spp., Candida krusei, and Candida glabrata

STD Product sheet
Molecular Requisition

Respiratory Testing (RPP)

A variety of viruses and some bacteria (pathogens) can cause infections of the respiratory tract. RPP testing through naspharyngeal swabs provides simultaneous qualitative detection and identification of multiple respiratory viruses and bacteria from patients whom are suspected for respiratory infections. Respiratory infections are increasing each year. According to the CDC the number of cases of influenza during 2018 was the highest since 2009.

  • RPP by PCR testing identifies causative organism/bacteria/pathogen by its DNA/RNA – which makes it possible to quickly diagnosis the type of infection.
  • RPP testing is a useful tool in avoiding over prescribing of antibiotics.
  • Average of 24-48 hour turn around time
  • Respiratory Panel includes the following:
    • Virus: Adenovirus, Bocavirus, Coronavirus 229E, Coronavirus HKU-1, Coronavirus NL63, Coronavirus OC43, Enterovirus, Influenza A, Influenza B, Metapneumovirus A/B, Parainfluenza Virus Type 1, Parainfluenza Virus Type 2, Parainfluenza Virus Type 3, Parainfluenza Virus Type 4, Parechovirus, Respiratory Syncytial Virus A/B, Rhinovirus,
    • Bacteria: Bordetella pertussis, Chlamydophila pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Legionella (pneumophila/longbeach), Moraxella catarrhalis, Mycoplasma pneumoniae, Salmonella spp, Staphylococcus aureus, Streptococcus pneumoniae

Respiratory Panel Product Sheet 

RPP sample report
Molecular Requisition

Nail Testing

Onychomycosis, the most common nail disease in the US, is a fungal infection of the fingernails or toenails that may involve any component of the nail unit, including the matrix, bed or plate. Treatment of onychomycosis is very expensive and requires long-term therapy, therefore, a proper diagnosis is needed.

  • Nail by PCR Testing identifies causative fungi by its DNA/RNA, which makes it possible to diagnosis onychomycosis accurately.
  • 48 hour turn around time (TAT), allowing for quicker treatment
  • Identifies poly-microbial infections
  • Accurate and reliable diagnosis (high sensitivity and specificity)
  • Nail Fungus Panel testing includes:
    • Acremonium strictum, Alternaria, Aspergillus niger, Aspergillus terreus, Candida albicans, Candida glabrata, Candida krusei, Candida lusitaniae Candida parapsilosis, Candida tropicalis, Epidermophyton floccosum, Fusarium solani, Microsporum audouinii, Microsporum canis, Neofusicoccum mangiferae, Trichophyton interdigitale and Trichophyton rubrum

Nail sample report
Molecular Requisition

Wound Testing

Traditional cultures fail to grow more than 85% of organisms identified in chronic wounds. Cultures also have limitations which render them almost irrelevant for the diagnosis of polymicrobial clinical and biofilm infections.

  • Wound testing by PCR Identifies causative organism/bacteria/pathogen by its DNA/RNA, which makes it possible to personalize antimicrobial therapy in wound care patients
  • 24-48 hour turn around time (TAT), allowing for quicker treatment
  • Identifies poly-microbial infections
  • Includes Resistance Gene Analysis to assist with therapeutic selection
  • >95% sensitivity and >95% specificity
  • Wound Panel includes testing of the following organisms:
    • Acinetobacter baumannii, Bacteroides spp., Citrobacter aerogenes, Enterobacter cloacae, Enterococcus faecalis, Enterococcus faecium, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Morganella morganii, Pseudomonas aeruginosa, Proteus mirabilis, Proteus vulgaris, Staphylococcus aureus, Streptococcus pyogenes

Wound Sample Report
Molecular Requisition

Gastrointestinal Testing

A variety of viruses, bacteria, and parasites can cause infections of the digestive system. Many are often caused by infesting food or fluid that has been contaminated by bacteria, viruses, or even parasites. The Stone Gastrointestinal Molecular Testing by PCR is the personalized solution for diagnosis of digestive system infections. The GI panel has improved patient care by rapidly identifying a broad range of pathogens, which may not have otherwise been detected, reducing the need for other diagnostic tests, reducing unnecessary use of antibiotics, and leading to a reduction in hospital length of stay.

  • Identifies causative organism/bacteria/pathogen by its DNA/RNA, which makes it possible to diagnosis GI infections accurately.
  • 24-48 hour turn around time (TAT), allowing for quicker treatment
  • Identifies poly-microbial infections that may have been missed with traditional testing
  • >95% sensitivity and >95% specificity
  • GI Panel includes testing of the following organisms:
    • Campylobacter, C. difficile Toxin A/B, Plesiomonas shigelloides, Salmonella, Vibrio, Vibrio cholera, Yersinia enterocolitica, Enteroaggregative E. coli, Enteropathogenic E. coli, Enterotoxigenic E. coli lt/st, Shig-like toxin-producing E., E. coli 0157, Shigella/Enteroinvasive E., Cryptosporidium, Cyclospora cayetanensis, Entamoeba histolytica, Giardia lamblia, Adenovirus F 40/21, Astrovirus, Norovirus GI/GII, Rotavirus A and Sapovirus

GI Sample Report
Molecular Requisition

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