PGx by Stone Labs is a pharmacogenetics test that can help predict how a patient will respond to drug therapy based on individual genetic makeup.

  • Recent research has linked a number of genes, including CYP2C19, CYP2C9, CYP2D6, and VKORC1, with an individual’s drug response. Single nucleotide polymorphisms (SNP) and copy number variations (CNVs) in these genes have been shown to influence the rate of drug metabolism. An extended panel of genes may help to guide clinical research for therapeutic treatment and response.
  • Obtain relevant data for 69 SNPs/INDELs in 20 genes, plus 5 CNVs in CYP2D6.
  • Use flexible throughput formats to accommodate varying sample throughput.
  • Get robust data reporting with interactive visualization for results management.
Pharmacogenetics is the study of the role of the genome in the body’s response to drugs. Its name (pharmaco + genomics) reflects the combination of pharmacology and genomics.

• CYP1A2

• CYP2B6
• CYP2C19
• CYP2C9
• CYP2D6

• CYP3A4
• CYP3A5
• F2
• F5


Pharmacogenomics in Cardiology

  • ACE Inhibitors
  • Angiotensin II Receptor Blockers (ARBs)
  • Antianginal Agent
  • Antiarrhythmic Agent
  • Anticoagulant
  • Antiplatelet
  • Beta Blockers
  • Calcium Channel Blockers
  • Diuretics
  • Phosphodiesterase Inhibitors
  • Antilipemic Agent(statins)
  • Vasodilators

Pharmacogenomics in Psychiatry

  • Aldehyde Dehydrogenase Inhibitors
  • Antianxiety Agents
  • Antidepressants
  • Antimanic Agents
  • Antipsychotics
  • Benzodiazepines
  • Tricyclic Antidepressants
  • Cannabinoids
  • SNRIs
  • SSRIs
  • Stimulants

Pharmacogenomics in Pain Management

  • Anesthetics
  • Central α-2 Adrenergic Agonists
  • Alpha2-Adrenergic Agonist
  • NSAIDs
  • Opioids
  • Opioids Antagonists
  • Serotonin Receptor Agonists
  • Skeletal Muscle Relaxant

Pharmacogenomics in Infectious Diseases

  • Antibiotics
  • Antimalarial Drugs
  • Antiviral Drugs
  • Protease Inhibitors

Pharmacogenomics in Neurology

  • Anticonvulsant Drugs
  • Barbiturates
  • COMT Inhibitors
  • Monoamine Depletors
  • Antimigraine Agent

Pharmacogenomics in Oncology

  • Taxane Derivative Antimetabolite
  • Platinum Analog
  • Alkylating Agent
  • Anthracycline
  • Chemotherapy
  • Modulating Agent
  • Urate-Oxidase
  • Estrogen Receptor Modulator
  • Kinase Inhibitor
  • Antiemetic Topoisomerase Inhibitors
  • Immunomodulators
  • Vinca Alkaloids
Associated drugs carry pharmacogenomics recommendations put forth by the Food and Drug Administration (FDA), European Medicines Agency (EMA), Clinical Pharmacogenetics Implementation Consortium (CPIC), Dutch Pharmacogenetics Working Group (DPWG), Pharmaceuticals and Medical Devices Agency, Japan (PMDA), and/or related pharmacogenomics publications.
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